1	Osteoporosis
2	OSTEOPOROSIS:Biomechanical Definition
3	How common is osteoporosis in the US? Osteoporosis threatens the health of 44 million people¹ 10 million with osteoporosis 34 million with low bone mass 80% are women¹
4
5	Osteoporosis in Women
6	How does osteoporosis stack up vs. other diseases in women?
7	Osteoporosis in Men
8	Osteoporosis World Wide
9
10	Hip fracture prevalence in the EU European Union (363 million inhabitants) 1997 Actual 400,000 women 100,000 men 2031 Estimate 600,000 women 150,000 men
11	Osteoporosis in China Large population in China: 1.3 billion Increased aging group ( age > 65): 88.11 million Postmenopausal women who are at the risk of osteoporosis : 129.7 million Living standards have changed. City population are increasing: City 36.09 % Rural 63.91%
12	Osteoporosis Disease
13
14
15
16
17	Risk of Dealth for Hip Fx in Women Compare to Other Disease
18	Comparative cost and mortality Annual direct cost in the U.S. Breast Cancer $ 6 billion¹ Osteoporosis $16 billion² More people die of osteoporosis-related hip fractures each year than die of breast cancer!
19	Diagnosis of Osteoporosis
20	Diagnosis of Osteoporosis (cont.)
21	Diagnosis of Osteoporosis (cont.)
22	Fracture are not diagnosed nor treated Less than 10% of distal forearm fractures or hip fractures are diagnosed or treated for OP Symptomatic treatment prevails Hospitals (ERs) are missing a new source of patients and revenue
23	The challenge of underdiagnosis Majority of people with osteoporosis are neither diagnosed nor treated Gallup survey of women ages 55-60 with osteoporosis ¹: 86% had never spoken with their doctors about osteoporosis prevention prior to their diagnosis. 2 to 3 undiagnosed patients for every 1 diagnosed ²
24	Treatment for Osteoporosis
25	Treatment for Osteoporosis (cont.)
26	Existing bone density technologies Single & Dual Photon Absorptiometry (SPA & DPA) Dual Energy X-ray Absorptiometry (DXA) Quantitative Computed Tomography (QCT) Radiographic Absorptiometry (RA) Radiogrammetry Ultrasound
27	Our solution OsteoGram (RA technology) A cost-effective, precise and accurate bone diagnostic technology which predicts risk of future hip fracture Uses existing standard x-ray equipment No large capital investment Automated, no special expertise required
28	History - OsteoGram Acquired the original technology in 1991 Central Lab for BMD testing in mid 90s Over 130,000 patients have been tested FDA clearance of automated system in 1999 Two US patents, total 40 claims cover the technology
29	DXA Vs Peripheral
30	Key benefits - OsteoGram Anytime, anywhere 24/7- no special certification needed Low capital investment Low cost Low radiation burden Predicts fracture risk Patented technology FDA, SDA cleared Compatible with existing DR and PACS Useful in ROW countries
31	Key strategies - OsteoGram OEM Digital x-ray manufacturers PACS companies Front-end workstation developers End users Medical specialists Primary care ER Rheumatologists Orthopaedic specialists Venues Rural hospitals Imaging centers Industrial/employee health
32	CompuMed Poised For Growth